Malaria in Pregnancy: Project Major Activity 7

A Randomized Open-Label Evaluation of the Antimalarial Prophylactic Efficacy of Azithromycin-Piperaquine versus Sulfadoxine-Pyrimethamine in Pregnant Papua New Guinean Women

Brioni R Moore, John M Benjamin, Roselyn Tobe, Maria Ome-Kaius, Gumul Yadi, Bernadine Kasian, Charles Kong, Leanne J Robinson, Moses Laman, Ivo Mueller, Stephen Rogerson, Timothy ME Davis

2019-10-01

Emerging malaria parasite sulfadoxine-pyrimethamine (SP) resistance has prompted assessment of alternatives for intermittent preve..

Microscopic and submicroscopic Plasmodium falciparum infection, maternal anaemia and adverse pregnancy outcomes in Papua New Guinea: A cohort study

HW Unger, A Rosanas-Urgell, LJ Robinson, M Ome-Kaius, S Jally, AJ Umbers, W Pomat, I Mueller, E Kattenberg, SJ Rogerson

2019-09-02

Background: Infection during pregnancy with Plasmodium falciparum is associated with maternal anaemia and adverse birth outcomes i..

Burden and impact of Plasmodium vivax in pregnancy: A multi-centre prospective observational study

A Bardají, FE Martínez-Espinosa, M Arévalo-Herrera, N Padilla, S Kochar, M Ome-Kaius, C Bôtto-Menezes, ME Castellanos, DK Kochar, SK Kochar, I Betuela, I Mueller, S Rogerson, C Chitnis, D Hans, M Menegon, C Severini, H del Portillo, C Dobaño, A Mayor

2017-06-12

Background: Despite that over 90 million pregnancies are at risk of Plasmodium vivax infection annually, little is known about the..

Effects of Plasmodium falciparum infection on umbilical artery resistance and intrafetal blood flow distribution: A Doppler ultrasound study from Papua New Guinea NCT01136850 NCT

M Ome-Kaius, S Karl, RA Wangnapi, JW Bolnga, G Mola, J Walker, I Mueller, HW Unger, SJ Rogerson

2017-01-19

Background: Doppler velocimetry studies of umbilical artery (UA) and middle cerebral artery (MCA) flow help to determine the prese..

Preterm or not - An evaluation of estimates of gestational age in a cohort of women from rural Papua New Guinea

S Karl, CSN Li Wai Suen, HW Unger, M Ome-Kaius, G Mola, L White, RA Wangnapi, SJ Rogerson, I Mueller

2015-05-06

Background: Knowledge of accurate gestational age is required for comprehensive pregnancy care and is an essential component of re..

Impact of intermittent preventive treatment in pregnancy with azithromycin-containing regimens on maternal nasopharyngeal carriage and antibiotic sensitivity of Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus: A cross-sectional survey at delivery

HW Unger, C Aho, M Ome-Kaius, RA Wangnapi, AJ Umbers, W Jack, A Lafana, A Michael, S Hanieh, P Siba, I Mueller, AR Greenhill, SJ Rogerson

2015-04-01

Sulfadoxine-pyrimethamine (SP) plus azithromycin (AZ) (SPAZ) has the potential for intermittent preventive treatment of malaria in..

Proinflammatory responses and higher IL-10 production by T cells correlate with protection against malaria during pregnancy and delivery outcomes

P Requena, D Barrios, LJ Robinson, P Samol, AJ Umbers, R Wangnapi, M Ome-Kaius, A Rosanas-Urgell, A Mayor, M López, E De Lazzari, M Arévalo-Herrera, C Fernández-Becerra, H Del Portillo, CE Chitnis, PM Siba, S Rogerson, I Mueller, A Bardají, C Menéndez

2015-04-01

Pregnancy triggers immunological changes aimed to tolerate the fetus. However, it has not been properly addressed whether similar ..